Silicate biomineralization  
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Although the formation of clays has long been considered as a purely abiotic process, an increasing number of studies has recently suggested the implication of microorganisms for some of them. Over the last years, we have been investigating silicate biomineralization through field sample studies and lab experiments.

Characterization of P species at the nanoscale








Charaterization of P species by scanning transmission x-ray microscopy (STXM):
- identification of P mineral through Ca and P speciation
(Ca & P L2,3 edges)
- Quantification of carbonate substitution (C K-edge)



                Benzerara et al (2004) Geobiology

                Cosmidis et al (2015) Acta Biomaterialia









Geochimical impact of polyphosphate and Fe-phosphate  formation



Role and mechanisms of Fe-phosphate biomineralization in Lake Pavin

                    Cosmidis et al (2014) Geochim. Cosmochim Acta
                    Busigny et al (2016) Book chapter


Massive formation of polyphosphate by some magnetotactic bacteria in Lake Pavin

                    Rivas-Lamelo et al (2017) Geochemical Perspective Letters



Molecular mechanisms of calcification





Kinetics and localization of calcification by E. coli mutants surexpressing alkaline phosphatase phoA

Cosmidis et al (2015) Frontiers in Earth Science

In silico and in vitro analysis of diverse phosphatases involved in calcification

                    Skouri-Panet et al (2018) Frontiers in Microbiology

Fossilization of bacterial cells by calcification





FIB/TEM/STXM characterization of bacterial fossils in phosphorites/coprolites...
                    Cosmidis et al (20013) Chemical Geology
                    Cosmidis et al (2013) Geobiology
                    Zaton et al (2015) Palaeogeography, Paleoclimatology, Palaeoecology

Medical calcifications





Nanoscale characterization of so-called nanobacteria/microcalcifications

Benzerara et al (2006) Journal of Investigative Medicine

Bacterial knvolvement in the formation of some kidney stones
                    Marine Livrozet's PhD

 

Nicolas MENGUY     Modifié le 06 juillet 2007